MYOXINOL ? LS 9736

THE VEGETAL ANSWER TO SMOOTH

EXPRESSION LINES

INCI NAME

Hydrolyzed Hibiscus Esculentus Extract(and)Dextrin

 

EXPRESSION LINES

There are 2 main mechanisms in wrinkle formation : biological (aging of cells,oxidation or glycation of macromolecule…) , and mechanical, when face muscles are involved .

Facial muscles are responsible for the formation of dynamic wrinkles: horizontal and vertical frown lines across the forehead, crow's feet around the eyes and “ nasolabial” lines around the mouth.

As long as biological aging mechanisms have not altered the skin's mechanical properties, these lines are reversible and the skin recovers a smooth appearance when facial muscles relax.

But when biological and mechanical factors are combined, the skin loses its elasticity and its ability to return to its initial state, prior to muscle contraction.

The dynamic wrinkles become permanent, generating “expression lines”

A recent advance in the cosmetic dermatology industry , Botox ? injections, offers to erase these dynamic wrinkles by inhibiting facial muscle contraction.

To answer the need for a topical, gentle alternative to drastic procedures, Laboratoires Serobiologiques have developed MYOXINOL ? LS 9736 , with targeted activity against expression lines.

MYOXINOL ? actually goes further , as its efficacy against mechanical parameters of aging is complemented by biological benefits, offering a comprehensive anti-wrinkle approach (patented).

DEFINITION / COMPOSITION

MYOXINOL? LS 9736 is a complex of oligopeptides obtained by biotransformation of native proteins from the seeds of Hibiscus esculentus L.(okra )

Hibiscus trees grow mainly in South Asia and Africa . Their seeds are widely used in traditional medicine, but also as a food source due to their high nutritional value.

SKIN BENEFITS

We have demonstrated the efficacy of oligopeptides from Hibiscus seeds to reduce muscle contraction ( in vitro demonstration), reducing the formation of expression lines.

This Botox? - like activity is complemented by efficacy against biological aging, helping to preserve optimal skin elasticity.

This comprehensive anti-aging approach is demonstrated by a long term clinical evaluation (topical application).

COSMATIC USE

- Facial anti-age.

- Topical answer to smooth expression lines.

- Eliminate or reduce frequency of invasive procedures.

EFFICACY TESTS

Inhibition of muscle cells contraction,in vitro

Innovative model mimicking the hyperactivity of facial muscles.

MYOXINOL ? LS 9736 significantly reduces muscle cells contraction.

This effect is longer lasting then the reference, completely reversible after 24 hours, yet providing evidence of the harmlessness of MYOXINOL ? on the long term.

MYOXINOL ? inhibits the mechanical factor responsible for expression lines apparition.

MYOXINOL? LS 9736 has shown good anti-free radical activity and has activated the natural defenses (reduced glutathione) of the cells against the deleterious effects of free radicals. MYOXINOL? prevents oxidative damage , thus protecting skin from biological aging

MYOXINOL? LS 9736 has a strong anti-wrinkle capacity, due to its ability to reduce facial muscle contraction via a topical application, combined with a protective efficacy towards oxidative stress.

Due its mechanisms of action, MYOXINOL ? LS 9736 particularly targets the prevention and smoothing of expression lines.

Complementary tests :

•  Anti-oxidant effect, in vitro.

•  Anti-wrinkle activity (clinical test ) , topical reduction.

•  26% wrinkle reduction (mean versus placebo).

 

Oligopeptides from Hibiscus esculentusseeds
to smooth expression lines

 

 

 

 

 

 

 

 

 

 

Higher Education Degrees